Sterilization of native proteins usually provokes physicochemical modifications
SPS® technologies effectively protect proteins during sterilization procedures and preserve protein structure and functionality
SPS® protect biologics during bulk and confectioned sterilization when applying β-, γ-irradiation or ethylene oxide (EtO)
SPS® technologies effectively protect biologics during different kinds of sterilization procedures like 25 kGy of β- (E-beam) or γ- irradiation (ISO 11137) or ethylene oxide (EtO) (ISO 11135).
The figure shows the example of an IgM antibody, coupled to a surface. Biologic activity was measured by an apoptosis induction assay.