Protection During Sterilization

Sterilization Procedures

  • Sterilization of native proteins usually provokes physicochemical modifications
  • SPS® technologies effectively protect proteins during sterilization procedures and preserve protein structure and functionality

SPS® protect biologics during bulk and confectioned sterilization when applying β-, γ-irradiation or ethylene oxide (EtO)

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SPS technology effectively protects biologics during different kinds of sterilization procedures like 25 kGy of - (E-beam) or - irradiation (ISO 11137)  or  ethylene oxide (EtO) (ISO 11135).

SPS® technologies effectively protect biologics during different kinds of sterilization procedures like 25 kGy of β- (E-beam) or γ- irradiation (ISO 11137) or ethylene oxide (EtO) (ISO 11135).

The figure shows the example of an IgM antibody, coupled to a surface. Biologic activity was measured by an apoptosis induction assay.